Chromosomal inversion Totally Explained

Everything about Chromosomal Inversion totally explained

An inversion is a chromosome rearrangement in which a segment of a chromosome is reversed end to end. An inversion occurs when a single chromosome undergoes breakage and rearrangement within itself. Inversions are of two types: paracentric and pericentric.
   Paracentric inversions don't include the centromere and both breaks occur in one arm of the chromosome. Pericentric inversions include the centromere and there's a break point in each arm. Cytogenetic techniques may be able to detect inversions, or inversions may be inferred from genetic analysis. Nevertheless, in most species small inversions go undetected. In insects with polytene chromosomes, for example Drosophila, preparations of larval salivary gland chromosomes allow inversions to be seen when they're heterozygous. This useful characteristic of polytene chromosomes was first advertised by Theophilus Shickel Painter in 1933.
   Inversions usually don't cause any abnormalities in carriers as long as the rearrangement is balanced with no extra or missing genetic information. However, in individuals which are heterozygous for an inversion, there's an increased production of abnormal chromatids (this occurs when crossing-over occurs within the span of the inversion). This leads to lowered fertility.
   Families that may be carriers of inversions may be offered genetic counseling and genetic testing.
   The most common inversion seen in humans is on chromosome 9, at inv(9)(p11q12). This inversion is generally considered to have no deleterious or harmful effects, but there's some evidence it leads to an increased risk for miscarriage for about 30% of affected couples.

Further Information

Get more info on 'Chromosomal Inversion'.

External Link Exchanges

Do you know how hard it is to get a link from a large encyclopaedia? Well we're different and will prove it. To get a link from us just add the following HTML to your site on a relevant page:

<a href="http://chromosomal_inversion.totallyexplained.com">Chromosomal inversion Totally Explained</a>

Then simply click through this link from your web page. Our crawlers will verify your link, extract the title of your web page and instantly add a link back to it. If you like you can remove the words Totally Explained and embed the link in article text.
As long as your link remains in place, we'll keep our link to you right here. Please play fair - our crawlers are watching. Your site must be closely related to this one's topic. Any kind of spamming, dubious practises or removing the link will result in your link from us being dropped and, potentially, your whole site being banned.